Am J Surg. 1957 Jun;93(6):1018-20. Melanoma arising in a cafÃ© au lait spot of neurofibromatosis. PERKINSON NG. PMID: 13424854; [Indexed for MEDLINE] .
A patient with neurofibromatosis and many â€œcafÃ© au lait spotsâ€ in whom melanocarcinoma developed in one of these spots which contained moderate junctional .
The case of a thirty-three year old woman who developed a malignant melanoma in what appeared to be a cafÃ©–au–lait spot is presented. Only one such case .
CafÃ©–au–lait spots are smooth, often irregular, brown spots on the skin. They are usually the earliest sign for neurofibromatosis. Ask a dermatologist!