CafÃ©–au–lait spots (Figure 121-1) are usually the first feature to appear; some may be present at birth, and they continue to develop and increase in size until puberty.
Cafe–au–lait spots are usually noticed in the first few weeks of life, or may appear earlier. Their absence in a newborn that is at risk of inheriting NF1 from a parent is not a good indication that the baby has not received the NF1 gene, since the spots may show up later. Neurofibromas are not often found in infancy.
cafÃ©–au–lait spots alone do not lead to any health problems but may be associated. Although they can appear at any age, neurofibromas most often develop.
They're usually benign (non-cancerous), and most often appear during puberty and. . Q: If my child has many cafÃ©–au–lait spots, does that mean that she will .
Define cafÃ© au lait spots typical of neurofibromatosis type 1 (NF1) and describe. Similarly, multiple patchy areas of hyperpigmentation can occur in healthy. to 14 years when they were noted to have six or more CAL spots and who were .